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Современные возможности лечения висцеральных метастазов у больных метастатическим кастрационнорефрактерным раком предстательной железы

Современные возможности лечения висцеральных метастазов у больных метастатическим кастрационнорефрактерным раком предстательной железы

Abstract

Лекарственны х препаратов, увеличивающих продолжительность жизни пациентов с метастатическим кастрационно-рефрактерным раком предстательной железы (КРРПЖ), на сегодняшний день недостаточно. За последние 3 года на фармацевтическом рынке появилось несколько новых препаратов, направленных на лечение прогрессирующего РПЖ. Абиратерона ацетат является ингибитором биосинтеза андрогенов и применяется в том числе для увеличения продолжительности жизни пациентов с метастатическим КРРПЖ, прогрессирующим после химиотерапии. Результаты лечения метастатического КРРПЖ зависят от ряда факторов. Висцеральные метастазы относятся к факторам неблагоприятного прогноза течения заболевания. Нами проведен анализ результатов лечения больных КРРПЖ с висцеральными метастазами с использованием абиратерона ацетата.

Medications increasing the survival of patients with metastatic castration-refractory prostate cancer (CRPC) are lacking today. In the past 3 years, in the pharmaceutical market there have been a few novel drugs to treat progressive prostate cancer. Abiraterone acetate is an androgen synthesis inhibitor, which is also used to increase the survival of patients with metastatic CRPC that progresses after chemotherapy. The results of treatment for metastatic CRPC depend on a number of factors. Visceral metastases are poor predictors of the course of the disease. The results of abiraterone acetate treatment were analyzed in CRPC patients with visceral metastases.

Keywords

КАСТРАЦИОННО-РЕФРАКТЕРНЫЙ РАК ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ,АБИРАТЕРОНА АЦЕТАТ,ВИСЦЕРАЛЬНЫЕ МЕТАСТАЗЫ

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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold