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Половые различия возрастной динамики минеральной плотности костной ткани у жителей Карелии

Половые различия возрастной динамики минеральной плотности костной ткани у жителей Карелии

Abstract

Проведен анализ динамики минеральной плотности костной ткани поясничных позвонков у 929 человек (740 женщин и 189 мужчин) в возрасте от 20 до 87 лет, проживающих на территории Карелии. Минеральная плотность оценивалась методом двухэнергетической рентгеновской абсорбциометрии. Выявлено, что величина значений пиковой костной массы у мужчин на 5% ниже значений базы денситометра, у женщин на 1,6%. Статистически значимое (p<0,05) снижение минеральной плотности позвонков у женщин выявлено в возрасте 41-45 лет, тогда как у мужчин в 51-55 лет. У женщин отмечалось неравномерное возрастное снижение костной массы в позвонках: 0,3% в год (с 40 до 50 лет), 0,8% в год (с 50 до 60 лет), 0,3 0,5% в год (с 61 до 75 лет), 0,7% в год (после 75 лет). У мужчин от 45 до 60 лет наблюдалось равномерное снижение костной массы (по 0,5% год), после 60 лет по 0,3% в год. Потеря минеральной плотности костной ткани позвонков в 75 лет у женщин составила 20%, у мужчин 11,1%.

The age-related changes of mineral density of lumbar vertebrae were analyzed in 929 (740 women and 189 men) patients aged from 20 to 87 living in Karelia. Bone mineral density was evaluated by dual x-ray absorptiometry. The values of mineral density peak in men were 5% lower and in women 1.6% in comparison with data of densitometer base. A significant decrease in bone mineral density of vertebrae in women began at the age of 41-45 years, in men 51-55 years. Women revealed the irregular reduction in bone mineral density of vertebrae: aged 40-50 years 0.3% per year, aged 50-60 years 0,8% per year, aged 61-75 years 0.3 0.5% per year, and after 75 years 0.7% per year. In men the reduction in bone mineral density was more regular: aged 45-60 years 0.5% per year, after 60 years 0.3% per year. Demineralization of vertebrae in women of 75 years was 20%, in men 11.1%.

Keywords

КОСТНАЯ ТКАНЬ, ПОЗВОНОЧНИК, ПОЯСНИЧНЫЕ ПОЗВОНКИ, АБСОРБЦИОМЕТРИЯ, ДЕНСИТОМЕТРИЯ, МИНЕРАЛИЗАЦИЯ, МИНЕРАЛЬНАЯ ПЛОТНОСТЬ КОСТНОЙ ТКАНИ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green