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Генитальные микоплазмы (Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium) в развитии осложнений беременности, родов и послеродового периода

Генитальные микоплазмы (Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium) в развитии осложнений беременности, родов и послеродового периода

Abstract

Проведен проспективный анализ течения беременности, родов и послеродового периода у 677 женщин, прошедших скрининговое обследование на наличие вульвовагинальной и цервикальной инфекции, а также течения раннего неонатального периода у их новорожденных. Генитальные микоплазмы во влагалище и цервикальном канале выявлены у 304 (44,9%) пациенток: Ureaplasma parvum у 40,2%, U. urealyticum у 7,1%, Mycoplasma hominis у 4,6%, M. genitalium у 0,6%. При этом у подавляющего большинства - 232 (76,3%) обследованных генитальные микоплазмы в нижних отделах генитального тракта сочетались с другими условно-патогенными микроорганизмами и лишь в 72 (10,6%) случаях были выделены в виде монокультуры или в сочетании только с Lactobacillus spp. Показано, что колонизация нижних отделов генитального тракта у беременных условно-патогенными микроорганизмами - важный фактор риска преждевременных родов, преждевременного излития околоплодных вод, рождения детей с низкой массой тела (менее 2500 г), послеродового эндометрита и раневой инфекции. В то же время очевидно, что генитальные микоплазмы не имеют существенного значения в патогенезе неблагоприятных исходов беременности, родов и послеродового периода у женщин и раннего неонатального периода у новорожденных.

Prospective analysis of the course of pregnancy, labor, and postpartum period was carried out in 677 women screened for vulvovaginal and cervical infections and the course of the early neonatal period in their newborns was analyzed. Genital mycoplasmas were detected in the vagina and cervical canal in 304 (44.9%) patients: Ureaplasma parvum in 40.2%, U. urealyticum in 7.1%, Mycoplasma hominis in 4.6%, and M. genitalium in 0.6%. Genital mycoplasmas in the lower genital tract were combined with other opportunistic infections in the overwhelming majority of patients in 232 (76.3%). Monocultures or combinations with only Lactobacillus spp. were isolated in just 72 (10.6%) cases. Colonization of the lower genital tract ofpregnant patients by opportunistic micro-organisms was an important risk factor for preterm delivery, preterm amniorrhea, delivery of small-for-date (<2500 g) babies, for postpartum endometritis and wound infection. On the other hand, it was obvious that genital mycoplasmoses were inessential for the pathogenesis of unfavorable outcomes ofpregnancy, labor, and postpartum period in women and of the early neonatal period in newborns.

Keywords

ГЕНИТАЛЬНЫЕ МИКОПЛАЗМЫ, ПРЕЖДЕВРЕМЕННЫЕ РОДЫ, ПРЕЖДЕВРЕМЕННОЕ ИЗЛИТИЕ ОКОЛОПЛОДНЫХ ВОД, ПОСЛЕРОДОВЫЕ ГНОЙНО-СЕПТИЧЕСКИЕ ОСЛОЖНЕНИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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