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Имеет ли значение вариант панкреатодуоденальной резекции при оценке функциональных результатов операции?

Имеет ли значение вариант панкреатодуоденальной резекции при оценке функциональных результатов операции?

Abstract

В работе представлена сравнительная оценка функциональных результатов 81 панкреатодуоденальной резекции (ПДР), 42 из которых (51,9 %) были выполнены в классическом варианте с дистальной резекцией желудка и 39 (48,1 %) – по методике с сохранением привратника. Показанием к операции у всех пациентов был рак головки поджелудочной железы и периампулярной области. При оценке трофологического статуса оперированных больных выявлено, что в обеих группах большинство пациентов восстанавливали дефицит массы тела к первому году после операции. Изучение эндокринной и экзокринной функций поджелудочной железы показало, что значимых различий при сравнении функциональных результатов ПДР с сохранением привратника и гастропанкреатодуоденальной резекции не выявлено. При отсутствии признаков прогрессирования опухоли и проведении заместительной ферментной терапии у пациентов с течением времени прослеживается тенденция к компенсации функциональных расстройств после перенесенной операции.

We compared functional results of two most common types of pancreatoduodenectomy performed for pancreatic head or periampullary cancer (n = 81). Forty-two patients (51,9 %) underwent Whipple procedure, or gastropancreatoduodenectomy (GPDE), and 39 (48,1 %) underwent pylorus-preserving pancreatoduodenectomy (PPDE). In both groups, the most patients recovered weight loss one year after surgery. Evaluation of endocrine and exocrine functions showed that functional results of both types of surgery were similar, without significant differences. In patients without tumor progression and appropriate treatment, there was a clear tendency to compensation of functional disorders after pancreatoduodenectomy.

Keywords

РАК ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ, ГАСТРОПАНКРЕАТОДУОДЕНАЛЬНАЯ РЕЗЕКЦИЯ, ПИЛОРУССОХРАНЯЮЩАЯ ПАНКРЕАТОДУОДЕНАЛЬНАЯ РЕЗЕКЦИЯ, ЭКЗОКРИННАЯ НЕДОСТАТОЧНОСТЬ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
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