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Превращения феррипротопорфирина IX гемоглобина в ультразвуковом поле

Превращения феррипротопорфирина IX гемоглобина в ультразвуковом поле

Abstract

Действие ультразвука на гемоглобин (Нв) приводит к образованию мет-гемоглобина (метНв), который при дальнейшем воздействии доходит до глобина и билирубина. На наличие возможности образования билирубина указывает превращение феррипротопорфирина IX с разрывом α-метеновой связи и последующим образованием CO и гидратированного электрона. С гемоглобином СО образует карбоксигемоглобин (карбоксиНв). Одновременно спирты в УЗ-поле способствуют образованию карбоксиНв и восстановлению метНв до дезоксигемоглобина (дезоксиНв), а также при наличии гидратированного электрона - к увеличению концентрации супероксида, что приводит к увеличению количества радикалов кислорода и дальнейшему превращению гемоглобина.

The effect of ultrasound on hemoglobin (Hb) leads to the formation of metHb that within the further exposure comes to globin and bilirubin. The transformation of ferriprotoporfirin IX with α-methene gap of relation and the subsequent formation of CO and hydrated electron points to the posiibility of bilirubin formation. Carboxyhemoglobin together with CO forms hemoglobin. At the same timeб alcohols in the ultrasonic field contribute to the formation of carboxyhemoglobin and restoration of metHb to dezoksiHb, as well as the hydrated electron increases the concentration of superoxide, which leads to an increase in oxygen radicals and further conversion of hemoglobin.

Keywords

ФЕРРИПРОТОПОРФИРИН IX,ПРОТОПОРФИРИН IX,ГЕММ,ГЕМОГЛОБИН,НВ,УЗ ПОЛЕ,КАРБОКСИГЕМОГЛОБИН,МЕТНВ,СПИРТЫ,РАДИКАЛЫ КИСЛОРОДА,БИЛИРУБИН,СУПЕРОКСИД,ОКСИД УГЛЕРОДА (II),ВОДОРОДА ПЕРОКСИД,FERRIPROTOPORFIRIN IX,PROTOPORPHYRIN IX,GEMS,HEMOGLOBIN,HB,ULTRASONIC FIELD,CARBOXYHEMOGLOBIN,METHB,ALCOHOLS,OXYGEN RADICALS,BILIRUBIN,SUPEROXIDE,CARBON MONOXIDE (II),HYDROGEN PEROXIDE

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold