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Выбор тактики лечения при конкурирующей патологии рака легкого и аортального клапана

Выбор тактики лечения при конкурирующей патологии рака легкого и аортального клапана

Abstract

Представлен клинический пример комбинированного лечения пациента со злокачественной опухолью верхней доли левого легкого и выраженным пороком аортального клапана. Сочетание тяжелой конкурирующей патологии всегда требуют тщательного подбора тактики лечения. Риск одномоментной операции сопряжен с высокими интраоперационными и ранними послеоперационными осложнениями. Предложенная тактика последовательного лечения в объеме протезирования аортального клапана с последующим выполнением стереотаксической гипо-фракционной лучевой терапии на зону S3 верхней доли левого легкого показала отдаленный результат, сопоставимый с радикальным хирургическим вмешательством на легком. Компенсация гемодинамических показателей в сочетании с полным локальным ответом на радиохирургическое лечение при сроке наблюдения 18 мес. демонстрирует индивидуальный адекватный выбор комбинированного лечения при сохранении высокого качества жизни.

We present a clinical case of step-by-step treatment of a patient with a tumor of the left lung upper lobe and a pronounced aortic valvular disease. The combination of concurrent pathologies always requires a thorough selection of the treatment approach. The risks of simultaneous surgical interventions are associated with high intraoperative and early postoperative complications. The selected approach of the stepwise treatment of aortic valve replacement followed by stereotactic hypofractionated radiation therapy has demonstrated the outcomes comparable to those of radical surgery. The compensation of hemodynamic parameters and a full local response during 18-month follow-up has confirmed the appropriateness of a patient-specific complex treatment approach, with a high quality of life maintained.

Keywords

ПРОТЕЗИРОВАНИЕ АОРТАЛЬНОГО КЛАПАНА, БИОЛОГИЧЕСКИЙ ПРОТЕЗ АОРТАЛЬНОГО КЛАПАНА, РАДИОХИРУРГИЯ РАКА ЛЕГКОГО, СТЕРЕОТАКСИЧЕСКАЯ КОНФОРМНАЯ ЛУЧЕВАЯ ТЕРАПИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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