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Прогнозирование эффективности контроля артериального давления при артериальной гипертензии, коморбидной с язвенной болезнью

Прогнозирование эффективности контроля артериального давления при артериальной гипертензии, коморбидной с язвенной болезнью

Abstract

In out-patient conditions patients with hypertension were investigated (n=99): of which the core group consisted of patients with hypertension (H) comorbid with peptic ulcer (PU) and the comparison group consisted of patients with isolated H. In all patients, assessed clinical features (age, level and stage of Н, stage and functional class of heart failure), the spectral indices of heart rate variability (HRV), the types of orthostatic responses and circadian blood pressure. Determination of prognostic criteria for effective control of blood pressure in population studied parameters was solved by constructing the equations of dividing functions. Prognostically significant parameters for effective control of blood pressure in the group of comorbid disease were age, total power HRV and the index of sympathoparasympatetic balance, the group isolated H diastolic blood pressure, total power HRV and the index of sympathoparasympatetic balance. Most significant parameter influencing the efficacy of blood pressure control rate was sympathoparasympatetic balance HRV, and the least powerful the diastolic blood pressure.

В амбулаторных условиях обследованы 99 пациентов в возрасте 54,9±13,1 лет с артериальной гипертензией (АГ), которые были разделены на две группы: основную (АГ, коморбидная с язвенной болезнью) и сравнения (изолированная АГ). У всех пациентов оценивали клинические признаки (возраст, степень и стадия АГ, стадия и функциональных класс сердечной недостаточности), спектральные показатели вариабельности сердечного ритма (ВСР), типы ортостатических реакций и суточных профилей артериального давления (АД). Определение прогностических критериев эффективного контроля АД по совокупности исследуемых показателей решалось с помощью построения уравнений разграничительных функций. Прогностически значимыми параметрами для эффективности контроля АД в группе коморбидной патологии явились возраст, общая мощность спектра и показатель симпатовагального баланса ВСР; в группе изолированной АГ диастолическое АД, общая мощность спектра и показатель симпатовагального баланса ВСР. Наиболее весомым параметром, влияющим на эффективность контроля АД оказался показатель симпатовагального баланса ВСР, а наименее весомым диастолическое АД.

Keywords

АРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯ, ЯЗВЕННАЯ БОЛЕЗНЬ, КОМОРБИДНОСТЬ, ЭФФЕКТИВНОСТЬ КОНТРОЛЯ АРТЕРИАЛЬНОГО ДАВЛЕНИЯ, АРТЕРіАЛЬНА ГіПЕРТЕНЗіЯ, ВИРАЗКОВА ХВОРОБА, КОМОРБіДНіСТЬ, ЕФЕКТИВНіСТЬ КОНТРОЛЮ АРТЕРіАЛЬНОГО ТИСКУ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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