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Коллагенолитическая активность сыворотки крови пациентов с болезнью Пейрони

Коллагенолитическая активность сыворотки крови пациентов с болезнью Пейрони

Abstract

Purpose : research of collagenolytic activity of blood serum at patients with Peyronie’s disease (PD) according to clinical state of patient and disease duration. Material and research methods. Complex examination with collecting the anamnesis of disease and complaints was performed at 76 patients with PD. Ultrasonography of penis was carried out to patients. The Collagenolytic Activity (CA) of blood serum of the surveyed persons was estimated on P. N. Sharayev’s method and co-authors. (1987). Results of research. The broad dispersion of indicators of CA of blood serum of patients with PD is revealed. Results of research testify that high the CA of blood serum of patients with PD testifies the acute inflammatory process, and low one shows the stage of stabilization and/or process synchronization with the expressed fibrous changes. Hence, the features of undertaken medical actions have to be coordinated with a disease stage.

Цель: исследование коллагенолитической активности сыворотки крови больных с болезнью Пейрони (БП) в соответствии с клиническим состоянием пациента и длительностью заболевания. Материал и методы исследования. У 76-ти пациентов с БП было проведено комплексное обследование со сбором анамнеза заболевания и жалоб. Пациентам проводили УЗИ полового члена (ПЧ). Коллагенолитическую активность (КА) сыворотки крови обследованных лиц оценивали по методу П.Н. Шараева и соавт. (1987). Результаты исследования. Выявлен широкий разброс показателей КА сыворотки крови больных БП. Результаты исследования свидетельствуют о том, что высокая КА сыворотки крови больных БП свидетельствует об остром течении воспалительного процесса, а низкая — о стадии стабилизации и/или хронизации процесса с выраженными фиброзными изменениями. Отсюда следует, что характер предпринимаемых лечебных мероприятий должен быть согласован со стадией заболевания.

Keywords

БОЛЕЗНЬ ПЕЙРОНИ, ПОЛОВОЙ ЧЛЕН, ФИБРОЗ, ВОСПАЛЕНИЕ, СЫВОРОТКА КРОВИ, КОЛЛАГЕНОЛИТИЧЕСКАЯ АКТИВНОСТЬ, PEYRONIE’S DISEASE

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average