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Аденомы гипофиза и их структура в крупном промышленном центре (г. Новокузнецк)

Аденомы гипофиза и их структура в крупном промышленном центре (г. Новокузнецк)

Abstract

In 1992 Kemerovo region in the Russian Federation was first admitted as the area with an extraordinary ecological situation. Living in Kuzbass is factor of risk of forming of different endocrine diseases, deterioration of reproductive health, high quantities of individual and population risks of oncologist pathology, high levels of invalidism of population at able-to-work age because of environment pollution and harmful work conditions. The present study includes 299 sick people with confirmed diagnosis of adenomas of pituitary in the endocrine department of the town hospital № 1 for the period from 1995 to 2007 that is complete selection. Adenomas of pituitary are more often detected at people at active ableto-work age. Adenomas of pituitary are more often diagnosed at women 87,0%. The overwhelming majority of adenomas of pituitary (74,0%) is detected at the age of 20-50. Because of this disease 99 people (33,1%) have different degree of loss of their working ability. In the structure of adenomas prolactinomas dominate (53,5%), on the frequency of meeting hormonally inactive adenomas are on the second place (32,1%), somatotrophinomas are rarely met (in 11,7%) and the rarest ones at the population on Novokuznetsk are corticotrophinomas (in 2,7%). On dimensions of adenomas of pituitary microadenomas predominate at 68,0% sick people. The relation microadenomas to macroadenomas is 17 : 22 at men and 187 : 73 at women.

Еще в 1992 г. впервые в Российской Федерации Кемеровская область была признана регионом с чрезвычайной экологической ситуацией. Проживание в Кузбассе является фактором риска формирования различных эндокринологических и нейроэндокринологических заболеваний, ухудшения репродуктивного здоровья, высоких величин индивидуальных и популяционных рисков онкологической заболеваемости в связи с загрязнением окружающей среды и вредными условиями труда. В исследование включены 299 больных с подтвержденным диагнозом аденомы гипофиза (АГ) за период с 1995 по 2007 г., что является сплошной выборкой. Наиболее часто АГ определялась у лиц трудоспособного возраста и у женщин (87,0%). Подавляющее большинство АГ (74,0%) установлено в возрасте от 20 до 50 лет. По данному заболеванию 99 (33,11%) человек имели разную степень утраты трудоспособности. В структуре аденом доминировали пролактиномы (53,5%), на втором месте гормонально неактивные аденомы (32,1%), соматотропиномы встречались реже, в 11,7%, и самыми редкими у населения г. Новокузнецка являлись кортикотропиномы 2,7%. По размерам среди АГ преобладали микроаденомы у 68,0% больных. Отношение микроаденом и макроаденом составило у мужчин 17 : 22, у женщин 187 : 73.

Keywords

АДЕНОМА ГИПОФИЗА, ВОЗРАСТ, ПОЛ, ПРОЛАКТИНОМА, СОМАТОТРОПИНОМА, КОРТИКОТРОПИНОМА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold