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Холинэстеразы: взгляд нейрофизиолога

Холинэстеразы: взгляд нейрофизиолога

Abstract

The review addresses issues of structure and functions of acetyland butyrylcholinesterases. Authors consider these enzymes not only as limiters of the neurotransmitter acetylcholine life span in synaptic cleft but also accounting for their putative non-synaptic functions. Particular emphasis has been placed on the possibility of correction of nerve system pathologies by way of modification of the activity of these enzymes.

Обзор посвящен вопросам строения и функции ацетилхолинэстеразы и бутирилхолинэстеразы. Авторы рассматривают эти два фермента не только с позиции их роли как «ограничителя» времени нахождения в синаптический щели нейромедиатора ацетилхолина, но и с учетом их несинаптических функций. Особое внимание в обзоре уделено возможности коррекции патологии нервной системы путем изменения активности этих ферментов.

Keywords

ацетилхолинэстераза, бутирилхолинэстераза, синаптическая передача, synaptic transmission.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average