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Белки острой фазы воспаления и макроглобулины при воспалительных процессах органов малого таза

Белки острой фазы воспаления и макроглобулины при воспалительных процессах органов малого таза

Abstract

В статье представлены результаты сравнительного исследование содержания иммуноглобулинов классов А, М и G, концентрации острофазовых белков ?-1-антитрипсина (АТ), лактоферрина (ЛФ), ?-2-макроглобупина (МГ) и ассоциированного с беременностью ?-2-гликопротеина (РАG), обладающих как свойствами белков острой фазы, так и иммунорегуляторными свойствами, в сыворотке крови больных при различных вариантах воспалительных процессов органов малого таза у женщин для уточнения особенностей патогенеза, а также для оценки эффективности исследуемых показателей при дифференциальной диагностике заболеваний. Выявлено, что концентрации всех изученных показателей, кроме АТ, изменяются, при этом, содержание ЛФ во всех группах повышается с различной степенью выраженности, а изменения МГ разнонаправленные в зависимости от тяжести и распространенности процесса, уровень РАG повышается только при распространенном деструктивном процессе.

The authors carried out a comparative study of the levels of immunoglobulins A, M, and G, concentrations of acute-phase ƒ-1-antitrypsin (AT), and also levels of lactoferrin (LF), ƒ-2-macroglobulin (MG) and pregnancy-associated ƒ-2glycoprotein (PAG), that possess both the properties of acute-phase proteins, and the immunoregulatory properties, in blood serum of patients with different variants of inflammatory processes of the genital organs in order to specify pathogenesis and to evaluate the efficacy of the indices under study for making a differential diagnosis of diseases. It was found that concentrations of all the indices, except AT, changed. While for LF, an increase of its level of various degrees was observed in all groups, in case of MG these changes may take various directions depending on the severity and spreading the process, and the PAG level decreased only in disseminated destructive process.

Keywords

ВОСПАЛЕНИЕ ПРИДАТКОВ МАТКИ, ДЕСТРУКЦИЯ, БЕЛКИ ОСТРОЙ ФАЗЫ, АЛЬФА-2-МАКРОГЛОБУЛИН, ЛАКТОФЕРРИН, АЛЬФА-1-АНТИТРИПСИН, ИММУНОГЛОБУЛИНЫ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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