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Цитомегаловирусная инфекция у детей

Цитомегаловирусная инфекция у детей

Abstract

This article gives an analysis of the literature data, illuminating the problem of cytomegalovirus (CMV) infection. It summarizes the current understanding of the impact of CMV on the course of pregnancy and intrauterine fetal development. The methods of rational diagnosis of pregnant females and infants are viewed. The results of clinical and laboratory examination of 23 children under 2.5 years with CMV infection and their mothers by virological and immunological diagnostic methods are presented. The article shows high therapeutic effect of hyperimmuneanticy to megalovirus immunoglobulin in combination with recombinant interferon in the treatment of active CMV infection.

В статье приводится анализ данных литературы, касающейся проблемы цитомегаловирусной (ЦМВ) инфекции. Обобщаются современные представления о влиянии ЦМВ инфекции на течение беременности и внутриутробное развитие плода. Рассматриваются методы рациональной диагностики у беременных и детей раннего возраста. Представлены результаты клинико-лабораторного обследования 23 детей в возрасте до 2,5 года с ЦМВ инфекцией и их матерей с применением вирусологических и иммунологических методов диагностики. Показан высокий терапевтический эффект гипериммунного антицитомегаловирусного иммуноглобулина в сочетании с рекомбинантным интерфероном в лечении активной формы ЦМВ инфекции.

Keywords

ЦИТОМЕГАЛОВИРУСНАЯ ИНФЕКЦИЯ, ЭТИОЛОГИЯ, БЕРЕМЕННОСТЬ, ДЕТИ РАННЕГО ВОЗРАСТА, ДИАГНОСТИКА, ЛЕЧЕНИЕ, ГИПЕРИММУНОГЛОБУЛИН, ВИФЕРОНОТЕРАПИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze
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