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Мониторинг врожденных пороков развития челюстно-лицевой области в условиях неблагоприятного воздействия факторов окружающей среды

Мониторинг врожденных пороков развития челюстно-лицевой области в условиях неблагоприятного воздействия факторов окружающей среды

Abstract

An ecological-population monitoring of congenital maxillofacial developmental anomalies (lip and palate cleft) through the example of the Krasnodar Territory with use of medical documentation, data of demographic statistics and ecological examinations according to the geoecological card of the Northern Caucasus and the Medical-ecological atlas of the Krasnodar Territory has been carried out. A method of the environment ecological state estimation considering quantitative values of polluting emissions from stationary sources in the atmospheric air, harmful substances as a part of sewage dumped in open reservoirs, territorial pesticide loadings on soil has been used. Lead (II) content in biological media of the parents of the children with congenital developmental anomalies has been estimated, it amounted to: in blood serum from 0.102 to 0.365 mg/dm 3; in saliva from 0.220 to 0.380; in gastric secretion from 0.180 to 0.273; in urine from 0.110 to 0.300; in hepatic exudate from 0.232 to 0.300 mg/dm 3. In blood of 60 % of the examined mothers and in 45 % of the children with congenital developmental anomalies, cadmium (II) content was 0.005 ± 0.001 mg/l. For the districts of the Krasnodar Territory, a statistical analysis of connections between the indicators of environmental contamination and frequencies of birth of children with congenital maxillofacial developmental anomalies has been made.

Проведен эколого-популяционный мониторинг врожденных пороков развития челюстно-лицевой области (ВПР ЧЛО) с использованием медицинской документации, данных демографической статистики и экологических экспертиз согласно геоэкологической карте Северного Кавказа и Медико-экологическому атласу Краснодарского края. Использован способ оценки экологического состояния окружающей среды, учитывающий количественные значения загрязненных выбросов от стационарных источников в атмосферный воздух, вредных веществ в составе сточных вод, сбрасываемых в открытые водоемы, территориальных пестицидных нагрузок на почву. Определено содержание свинца (II) в биосредах родителей детей с ВПР ЧЛО, оно составляло: в сыворотке крови 0,102-0,365 мг/ дм 3; слюне 0,220— 0,380; желудочном секрете 0,180— 0,273; моче 0,110—0,300; печеночном экссудате 0,232—0,300. В крови у 60 % обследованных матерей и 45 % детей с ВПР ЧЛО кадмия (II) содержалось (0,005 ± 0,001) мг/л. Для районов Краснодарского края проведен статистический анализ связей между показателями загрязнения окружающей среды и частотой рождения детей с ВПР ЧЛО.

Keywords

СONGENITAL DEVELOPMENTAL ANOMALIES, ВРОЖДЕННЫЕ ПОРОКИ РАЗВИТИЯ, ЧЕЛЮСТНОЛИЦЕВАЯ ОБЛАСТЬ, ТЯЖЕЛЫЕ МЕТАЛЛЫ, БИОКОНТАМИНАЦИЯ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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