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Фармакоэкономический анализ иммуногистохимической диагностики HER2-статуса и таргетной терапии при раке молочной железы

Фармакоэкономический анализ иммуногистохимической диагностики HER2-статуса и таргетной терапии при раке молочной железы

Abstract

Статья посвящена анализу выраженности экспрессии HER2 при раке молочной железы в различных возрастных группах с оценкой стоимости реактивов для иммуногистохимической диагностики HER2 и лекарственных препаратов для последующей таргетной терапии герцептином. Проведенное исследование показало, что высокие затраты на таргетную терапию пациентов с раком молочной железы герцептином оправдывают широкий скрининг HER2, а минимизация затрат на иммуногистохимическую диагностику может быть проведена за счет исключения из скрининга пациентов с явными противопоказаниями для назначения этого лекарственного средства.

The article is devoted to the analysis of HER2 expression in breast cancer in different age groups and estimation of the cost of reagents for immunohistochemical diagnosis of HER2 and medicines for subsequent target therapy with herceptin. The conducted study has shown that the high cost of target therapy with herceptin in patients suffering from breast cancer covers HER2 screening expenses. Immunohistochemical diagnosis cost minimization can be achieved by exclusion from the screening of patients with apparent contraindications for the administration of this drug.

Keywords

РАК МОЛОЧНОЙ ЖЕЛЕЗЫ, ИММУНОГИСТОХИМИЧЕСКАЯ ДИАГНОСТИКА, ТАРГЕТНАЯ ТЕРАПИЯ, СТОИМОСТЬ РЕАКТИВОВ И ТАРГЕТНОЙ ТЕРАПИИ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
Related to Research communities
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