
Th ere has been presented the review of the scientifi c publications about relationship of induced radiation chromosomal aberrations and genetic polymorphism of xenobiotic biotransformation enzymes and DNA reparation over a 2000-2011 years. It has been revealed that in the conditions of radiation infl uence in vivo and in vitro with a higher level of chromosome aberrations in blood lymphocytes various polymorphic genetic markers are associated.
Выполнен обзор научных публикаций, посвященных анализу взаимосвязи между индуцированными радиацией хромосомными аберрациями и полиморфизмом генов ферментов биотрансформации ксенобиотиков и репарации ДНК в период за 2000-2011 гг. Выявлено, что в условиях воздействия радиации in vivo и in vitro с повышенным уровнем хромосомных аберраций в лимфоцитах крови ассоциированы разные полиморфные генетические маркеры.
ХРОМОСОМНЫЕ АБЕРРАЦИИ, ПОЛИМОРФИЗМ ГЕНОВ ФЕРМЕНТОВ БИОТРАНСФОРМАЦИИ КСЕНОБИОТИКОВ И РЕПАРАЦИИ ДНК
ХРОМОСОМНЫЕ АБЕРРАЦИИ, ПОЛИМОРФИЗМ ГЕНОВ ФЕРМЕНТОВ БИОТРАНСФОРМАЦИИ КСЕНОБИОТИКОВ И РЕПАРАЦИИ ДНК
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