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Клинико-морфологические особенности хромаффинных опухолей

Клинико-морфологические особенности хромаффинных опухолей

Abstract

We studied clinical features in 30 patients with tumors of chromaffin tissue (CTT). The results are compared with data on morphological research of the removed tumor, which is carried out using the scale scoring PASS. Among all CTT in our research 30% verified pheochromocytoma with potentially aggressive with the amount of points on the scale PASS from 4 to 8. It turned out that there were no statistically significant differences in the gender ratio, age, the number of patients with latent disease, hormonal activity, and tumor size and its density in the group of patients with benign pheochromocytoma (group 1) and in the group with potentially aggressive tumor (group 2). It was found that there was 2 times less patients with "classic" paroxysmal form of the arterial hypertension in group 2, persistent and mixed forms prevailed, and the number of heterogeneous neoplasms in CT was statistically significantly higher.

Изучены особенности клинической картины у 30 больных опухолях хромаффинной ткани. Результаты сопоставлены с данными морфологического исследования удаленной опухоли, которое проведено с применением шкалы балльной оценки PASS. Среди ОХТ в 30% верифицированы феохромоцитомы с потенциально агрессивным течением с суммой баллов по шкале PASS от 4 до 8. Оказалось, что гендерное соотношение, возраст, количество пациентов со скрытым течением заболевания, гормональная активность, а также размеры опухоли и ее плотность в группе пациентов с доброкачественными феохромоцитомами (1 группа) и с потенциально агрессивным течением (2 группа) статистически значимых различий не имели. Обнаружено, что в 2 группе в 2 раза меньше пациентов с «классической» пароксизмальной формой течения артериальной гипертонии, преобладают персистирующая и смешанная, а количество гетерогенных образований по данным КТ было статистически значимо выше.

Keywords

ФЕОХРОМОЦИТОМА, ФЕОХРОМОБЛАСТОМА, ШКАЛА ОЦЕНКИ ПОТЕНЦИАЛА ЗЛОКАЧЕСТВЕННОСТИ ОПУХОЛИ PASS, АДРЕНАЛЭКТОМИЯ, PHEOCHROMOCYTOMA OF THE ADRENAL GLAND SCALED SCORE (PASS)

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold