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Сравнительная клинико-морфологическая оценка результатов хирургического лечения ИБС у больных сахарным диабетом типа 2 и у пациентов без нарушений углеводного обмена

Сравнительная клинико-морфологическая оценка результатов хирургического лечения ИБС у больных сахарным диабетом типа 2 и у пациентов без нарушений углеводного обмена

Abstract

Проведено клинико-морфологическое сравнение результатов шунтирования коронарных артерий у 30 пациентов ишемической болезнью сердца в сочетании с сахарным диабетом типа 2 и 30 человек без нарушений углеводного обмена, подвергшихся операции АКШ. По данным морфологического исследования биопсийного материала миокарда левого желудочка, получено, что у пациентов СД более выражена и чаще встречается эндотелиальная дисфункция, гиперхромия ядер, уменьшение количества функционирующих капилляров и экспрессии рецепторов к инсулину через 6-12 месяцев после АКШ. Таким образом, получены морфофункциональные признаки изменений в миокарде, на основании которых возможно осуществлять прогноз течения атеросклероза и функционирования аортокоронарных кондуитов у больных с сахарным диабетом типа 2.

Clinical-morphological estimation of coronary arteries bypass results have been conducted in 60 patients with IHD undergone coronary artery bypass grafting (CABG). 30 patients have diabetes 2 and 30 patients dont have infringements of the carbohydrate exchange. Morphological researches of myocardium left ventricle biopsy material showed more expressive and more frequent endothelial dysfunction, nucleus hyperchromia, and also decrease of quantity of functioning capillaries, and insulin receptors expression in diabetic patients after 6-12 months after CABG. A discovered morphological myocardial change is foretelling prognosis of atherosclerosis and artery bypass function in patients with IHD and diabetes 2 types.

Keywords

сахарный диабет 2-го типа, аортокоронарное шунтирование, кондуиты, микроциркуляторное русло, инсулиновые рецепторы

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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