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Цитопротективный эффект урсодеоксихолевой кислоты на слизистую оболочку органов гастродуоденальной зоны у больных пожилого возраста с сочетанием желчнокаменной болезни и язвенной болезни двенадцатиперстной кишки

Цитопротективный эффект урсодеоксихолевой кислоты на слизистую оболочку органов гастродуоденальной зоны у больных пожилого возраста с сочетанием желчнокаменной болезни и язвенной болезни двенадцатиперстной кишки

Abstract

Проведено клинико-морфологическое исследование у больных пожилого возраста с сочетанием желчнокаменной болезни и язвенной болезни двенадцатиперстной кишки. Показано, что длительная урсотерапия не оказывает отрицательного влияния на клиническое течение язвенной болезни двенадцатиперстной кишки, не вызывает ее обострений у больных пожилого возраста. Данные гистологического исследования гастро- и дуоденобиоптатов на фоне лечения демонстрируют положительное влияние урсодеоксихолевой кислоты (УДХК) на слизистую оболочку желудка и двенадцатиперстной кишки с частичным восстановлением ее структуры, что обусловлено ее цитопротективным эффектом.

Was made a clinical-morphological study of elderly patients with a combination of cholelithiasis and duodenal ulcer. Was shown that prolonged ursoterapiya does not adversely affect the clinical course of duodenal ulcer, does not cause exacerbations of her elderly patients. These histological study of gastroesophageal and duodenobiop-tatov during treatment showed a positive effect of the ursodeoxycholic acid (UDCA) on the mucous membrane of the stomach and duodenum with the partial restoration of its structure, due to its cytoprotective effect.

Keywords

УРСОДЕОКСИХОЛЕВАЯ КИСЛОТА, СЛИЗИСТАЯ ОБОЛОЧКА ЖЕЛУДКА И ДВЕНАДЦАТИПЕРСТНОЙ КИШКИ

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze