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Состояние репродуктивной функции самцов белых крыс в условиях недостатка питательных веществ

Состояние репродуктивной функции самцов белых крыс в условиях недостатка питательных веществ

Abstract

Целью настоящей работы было исследование эффектов недостатка питательных веществ на функциональное состояние разных звеньев репродуктивной системы. Самцов белых крыс содержали на специальной диете в течение 30 дней. Усиление гемолиза эритроцитов в экспериментальных условиях свидетельствует о развитии окислительного стресса. В условиях недостатка питательных веществ имеет место усиление процессов перекисного окисления липидов в ткани семенников и гипоталамической ткани. Относительные массы гонад и гипофиза были снижены к концу экспериментальных воздействий в соответствии с коэффициентом положительной корреляции r = +0,461. Количество дефективных форм эпидидимальных сперматозоидов возросло более чем в 4,5 раза по сравнению с контролем. Ведущими патологиями были облом и потеря хвоста сперматозоидов. Таким образом, угнетение функционального состояния семенников связано с усилением процессов липопероксидации в системе гипоталамус-гипофиз-семенники.

The purpose of the paper is to study effects of deficiency in nutrients on different units of reproductive system. White male rats were fed with the special diet during 30 days. Erythrocyte haemolysis increase under experimental conditions allows us to conclude that the oxidative stress development takes place. Under conditions of deficiency in nutrients lipid peroxidation acceleration in testicular and hypothalamic tissues has been found to take place. Relative weights of gonads and pituitary were decreased to the end of experimental influence in accordance with the positive correlation coefficient r = +0,461. The total number of defective epididymal spermatozoa has been found to decrease by more than 4,5 times compared to the control. The leading pathologies were broken and lost tails of spermatozoa. Thus, functional state suppression in testes is connected with lipid peroxidation intensification in the system hypothalamus-pituitary-testes.

Keywords

ПЕРЕКИСНОЕ ОКИСЛЕНИЕ ЛИПИДОВ, МАЛОНОВЫЙ ДИАЛЬДЕГИД, ГИПОТАЛАМУС, СЕМЕННИКИ, ЭПИДИДИМАЛЬНЫЕ СПЕРМАТОЗОИДЫ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold