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Состояние внеклеточного матрикса кожи экспериментальных животных при удлинении голени по Илизарову

Состояние внеклеточного матрикса кожи экспериментальных животных при удлинении голени по Илизарову

Abstract

A complex study of the content and distribution of different glycosaminoglycane classes in the skin integument tissues of the leg being lengthened by the Ilizarov method has been performed. It has been revealed that fibrillogenesis signs appear in derma in the period of distraction, and the fibrillogenesis peak takes place in the period of fixation. The content of glycosaminoglycanes in epidermis and skin derivatives varies that is associated with the changes in the proliferative and biosynthetic activity of these structures in different experimental periods.

Проведено комплексное исследование содержания и распределения различных классов гликозаминогликанов в тканях кожного покрова голени, удлиняемой методом Илизарова. Выявлено, что в период дистракции в дерме появляются признаки фибриллогенеза, пик которого приходится на период фиксации. Отмечены вариации содержания гликозаминогликанов в эпидермисе и дериватах кожи, связанные с изменением пролиферативной и биосинтетической активности клеток этих структур в разные периоды эксперимента.

Keywords

КОЖНЫЙ ПОКРОВ, ЧРЕСКОСТНЫЙ ДИСТРАКЦИОННЫЙ ОСТЕОСИНТЕЗ, ГЛИКОЗАМИНОГЛИКАНЫ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold