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Отдаленные результаты применения пробиотиков и бальнеотерапии в комплексном лечении бактериального вагиноза. Сравнительное исследование

Отдаленные результаты применения пробиотиков и бальнеотерапии в комплексном лечении бактериального вагиноза. Сравнительное исследование

Abstract

Оценена эффективность применения пробиотика, содержащего лактобактерии easeir hamnosus spp. в виде живой культуры, и бальнеотерапии (грязь и рапа озера Эльтон) в рамках комплексного лечения бактериального вагиноза (БВ). Обследованы 107 пациенток, среди которых 51 на 2-м этапе лечения применяли пробиотик в виде вагинальных капсул, а 56 бальнеологические факторы озера Эльтон в виде грязевых тампонов с последующим орошением влагалища сильносульфидным солевым раствором (рапой). Для оценки эффективности лечения проводился анализ жалоб, данных объективного осмотра, рН-метрии, микроскопии, бактериологического исследования и ПЦР в «режиме реального времени» с использованием тест-системы «Фемофлор-16». После применения бальнеологических факторов на 2-м этапе лечения БВ выявлено значительное повышение пула лактобактерий в отдаленном периоде после лечения, что в 2,5 раза превышало данный показатель после применения традиционных методов восстановления микробиоты вагинального тракта с применением пробиотика (Р. < 0,01).

The efficacy of probiotics, containing lactobacillus сaseir hamnosus spp., and balneotherapy in comprehensive treatment of bacterial vaginosis (BV) was evaluated. 107 patients were examined. 51 patients were given probiotics and 56 patients were treated with balneological factors (mud and brine) after receiving Imidazole antimicrobial therapy Complaints, data of objective examination, pH-metry, smear microscopy, bacteriological investigation and a semiquantitative method of a real-time polymerase chain reaction were analyzed to evaluate the efficiency of treatment. After balneological treatment at its second stage, a considerable increase in lactobacillus pool was revealed in a long-term perspective. It was 2.5 times higher than that after probiotics (p < 0,01) were used in conventional treatments to restore the vaginal tract.

Keywords

БАКТЕРИАЛЬНЫЙ ВАГИНОЗ,КОМПЛЕКСНОЕ ЛЕЧЕНИЕ,ПРОБИОТИКИ,МИКРОБНЫЕ БИОПЛЕНКИ,БАЛЬНЕОЛОГИЧЕСКИЕ ФАКТОРЫ,BACTERIAL VAGINOSIS,COMPREHENSIVE TREATMENT,PROBIOTICS,MICROBIAL BIOFILMS,BALNEOTHERAPY

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
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