
The content of prekallikrein, activity of kallikrein and the total arginine esterase activity were studied in samples of tissue of benign (cystadenoma, n=20), malignant ovarian tumors (stage III cystadenocarcinoma, n=35), and ovaries removed during the operation on hysteromyoma (conventionally intact, n=18). In the malignant ovarian tumor tissue, activation of kallikrein-kinine system was manifested, with higher content of precursors and altered ratio of components. It should be noted that there are no distinctions between the indicators under study in the contralateral undamaged ovaries and those in the paired ovaries affected by malignant tumor.
В образцах ткани доброкачественных (цистаденомы, n=20), злокачественных опухолей яичников (цистаденокарциномы IIIстадии, n=35), яичников, удаленных во время операции по поводу миомы матки (условно интактные, n=18) изучали содержание прекалликреина, активность калликреина и общую аргининэстеразную активность. В ткани злокачественной опухоли яичников показана активация калликреин-кининовой системы с увеличением содержания предшественников и нарушением соотношения компонентов. Следует отметить отсутствие различий исследуемых показателей в контралатеральных непораженных яичниках от показателей в пораженном злокачественной опухолью парном яичнике.
КАЛЛИКРЕИН-КИНИНОВАЯ СИСТЕМА, ДОБРОКАЧЕСТВЕННЫЕ И ЗЛОКАЧЕСТВЕННЫЕ ОПУХОЛИ ЯИЧНИКОВ
КАЛЛИКРЕИН-КИНИНОВАЯ СИСТЕМА, ДОБРОКАЧЕСТВЕННЫЕ И ЗЛОКАЧЕСТВЕННЫЕ ОПУХОЛИ ЯИЧНИКОВ
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