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Сезонные изменения активности тканевых ферментов

Сезонные изменения активности тканевых ферментов

Abstract

In scientific work we have investigated the activity indexes of some enzymes of carbohydrate – energy and protein metabolism in blood of children and teenagers. The objects of research were children and teenages in the city of Makhachkala. To carry out the research in the age aspect 70 learners of 9, 11, 13, 14 and 17 years old were selected. When compared in autumn and spring the activity of the both general and isozyme lactate dehydrogenise in the blood of non-adults a specific law in changing of these figures is observed. This law is reflected in the fact that the activity of general lactate dehydrogenise in autumn period is notably higher in the investigated age periods. The results of the research on defining glucose6-phosphate dahydrogenase in blood serum of non-adults in autumn and spring showed the highest level of the enzyme activity at the age of 9. At the age of 11 a considerable glucose-6-phosphate dehydrogenise activity decreasing much more than in autumn. In teenagers of 13 and 14 in autumn the glucose-6-phosphate dehydrogenise activity increases considerably compared to the previous age group. In teenagers of 13 the activities of glucose-6-phosphate dehydrogenise increases in spring. At the age of 17 the activity of this enzyme decreases again (p 0,05) compared to 14-year-old teens and makes in autumn 20,1 ± 1,1 mE/L and spring – 19,5 ± 1,5 mE/L. The results of the research on defining alphaamylase activity in different age period show that the activity in the blood of non adults both in autumn and spring suffers non essential changes.

В научной работе мы исследовали показатели активности некоторых ферментов углеводно-энергетического и белкового обменов в крови у детей и подростков. Объектами исследования были дети и подростки, проживающие в городе Махачкале. Выполнены исследования в возрастном аспекте на 70 учениках в возрасте 9, 11, 13, 14 и 17 лет, специально подобранных. При сравнении осенью и весной активности как общей, так и изоферментов лактатдегидрогеназы в крови у невзрослых наблюдается определенная закономерность в изменении этих показателей. Эта закономерность отражается в факте, что активность общей лактатдегидрогеназы в осенний период значительно выше в исследуемые возрастные периоды. Результаты исследования по определению глюкозо-6-фосфатдегидрогеназы в сыворотке крови у невзрослых осенью и весной показали наивысший уровень активности фермента в возрасте 9 лет. В возрасте 11 лет отмечалось значительное уменьшение активности глюкоза-6-фосфатдегидрогеназы; весной активность этого фермента уменьшилась больше, чем осенью. У подростков 13 и 14 лет осенью активность глюкозо-6-фосфатдегидрогеназы значительно увеличивается по сравнению с предыдущей возрастной группой. У подростков 13 лет активность глюкозо-6-фосфатдегидрогеназы увеличивается весною. В возрасте 17 лет активность этого фермента уменьшается опять (р

Keywords

ДЕТИ, ПОДРОСТКИ, ОБЩАЯ И ИЗОФЕРМЕНТЫ ЛАКТАТДЕГИДРОГЕНАЗЫ, ГЛЮКОЗО-6-ФОСФАТДЕГИДРОГЕНАЗА, АЛАНИНАМИНОТРАНСФЕРАЗА, АСПАРТАТАМИНОТРАНСФЕРАЗА, АЛЬФА-АМИЛАЗА

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold