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Использование иммуномодулятора тимодепрессин в терапии идиопатических воспалительных миопатий

Использование иммуномодулятора тимодепрессин в терапии идиопатических воспалительных миопатий

Abstract

Идиопатические воспалительные миопатий (ИВМ) системные аутоиммунные заболевания, в клинической картине которых преобладают симптомы поражения скелетной мускулатуры преимущественно проксимальных отделов конечностей. Изучено влияние комбинированной терапии с включением препарата тимодепрессин на клиническое течение, электрофизиологические и иммунологические показатели у 15 пациентов с ИВМ. Динамика клинических, электрофизиологических и иммунологических данных свидетельствует о снижении активности аутоиммунного воспаления. Показано, что тимодепрессин оказывает при данной патологии иммуномодулирующее действие, сопровождающееся положительным клиническим эффектом. Библиогр. 14 назв. Ил. 5. Табл. 3.

Idiopathic inflammatory myopathies (IM) are system autoimmune diseases in whose clinical picture the symptom development of atrophia and paralysis of predominantly hand and leg muscles prevails. The influence of the combined therapy with inclusion of Thymodepressin preparation on clinical current, electrophysiological and immunological parameters of 15 patients with IM is studied. The dynamics of clinical, electrophysiological and immunological data testifies the decrease of autoimmune inflammation activity. It is shown that Thymodepressin renders immunomodulation effect at the given pathology accompanied by positive clinical effect.

Keywords

ИДИОПАТИЧЕСКИЕ ВОСПАЛИТЕЛЬНЫЕ МИОПАТИЙ, ДЕРМАТОМИОЗИТ, ПОЛИМИОЗИТ, ЦИТОКИНЫ, ТИМОДЕПРЕССИН

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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