Isoniazidinduceret toksisk hepatitis
Isoniazidinduceret toksisk hepatitis
Hepatotoxicity is a well-known side effect to isoniazid treatment with the risk of progression to liver failure. This case report describes a 39-year-old male, who received standard isoniazid treatment for latent TB infection (LTBI) and developed severe isoniazid-induced acute hepatitis. Liver transplantation was considered, but the patient slowly recovered with full hepatic regeneration. With increasing focus on treating LTBI in Denmark, routine follow-up including biochemical monitoring should be implemented for patients receiving LTBI treatment to prevent severe complications.
- University of Copenhagen Denmark
Adult, Male, Antitubercular Agents/adverse effects, Hepatitis/drug therapy, Humans, Isoniazid/adverse effects, Latent Tuberculosis/drug therapy
Adult, Male, Antitubercular Agents/adverse effects, Hepatitis/drug therapy, Humans, Isoniazid/adverse effects, Latent Tuberculosis/drug therapy
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