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Роль эритропоэтина в реализации межклеточных взаимодействий в крови у больных с терминальной стадией хронической почечной недостаточности

Authors: Osikov, M. V.; Grigoryev, T. A.; Maslennikova, N. P.;

Роль эритропоэтина в реализации межклеточных взаимодействий в крови у больных с терминальной стадией хронической почечной недостаточности

Abstract

Проведен анализ влияния эритропоэтина на межклеточные взаимодействия в крови у 50 больных с терминальной стадией хронической почечной недостаточности, находящихся на гемодиализе. У больных хронической почечной недостаточностью зафиксировано угнетение взаимодействий тромбоцитов друг с другом, с эритроцитами, с лимфоцитами и активация тромбоцитарно- нейтрофильных и тромбоцитарно-моноцитарных взаимодействий в периферической крови. To analyze influence of erythropoietin on cellcell interaction in blood of CRF dialyzed patients (n = 50) RESULTS: haemodialyzed CRF patients displayed diminished interaction of platelets with erythrocytes and lymphocytes. Platelet-platelet interactions were also depressed. On the contrary, platelet-neutrophil and platelet-monocyte interactions were stimulated. Осиков М.В., доктор медицинских наук, профессор кафедры патофизиологии, Челябинская государственная медицинская академия (Челябинск); тел.: 8-351-2627823; e-mail: mvo2003@list.ru Osikov M.V., the doctor of medical sciences, professor of department of physiopathology of the Chelyabinsk State Medical Academy (Chelyabinsk); ph.: 8-351-2627823; e-mail: mvo2003@list.ru. Масленникова H.IL, врач клинической лабораторной диагностики I категории, Челябинская областная детская клиническая больница (Челябинск); тел.: 8-9193119628; e-mail: Maslennikova- 351 @yandex.ru Maslennikova N.P., regional child s hospital, clinical laboratory. Doctor of clinical laboratory diagnostic category I. (Chelyabinsk); ph.: 8-9193119628; e-mail: Maslennikova-351 @yandex.ru. Григорьев Т.А., заочный аспирант кафедры патофизиологии, Челябинская государственная медицинская академия (Челябинск); тел: 8-9058325090; e-mail: ayalll@mail.ru Grigoryev T.A., post-graduate student of chair of pathological physiology of the Chelyabinsk State Medical Academy (Chelyabinsk); ph.: 8-9058325090; e-mail: ayalll@mail.ru

Keywords

haemodialysis, ГРНТИ 76.29, УДК 616.61-008.64-036.12-025.38.033.1, blood, chronic renal failure, cell-cell interaction, межклеточные взаимодействия в крови, диализ, хроническая почечная недостаточность, erythropoietin, эритропоэтин, УДК 616.61-008.6-036

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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