Pathological mechanisms of polyglutamine disorder in Drosophila model of Huntington disease

LIN, Yu-Hsien

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Doctoral thesis . 2020

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Pathological mechanisms of polyglutamine disorder in Drosophila model of Huntington disease

descriptionPublicationkeyboard_double_arrow_right Doctoral thesis 01 Jan 2020 Czech Republic English

Authors: LIN, Yu-Hsien;

Pathological mechanisms of polyglutamine disorder in Drosophila model of Huntington disease

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Abstract

The first publication in my thesis surveyed the impacts of adenosine homeostasis and its underlying mechanisms in Huntington disease (HD) pathogenesis using a Drosophila model. In the second publication, we have extended the use of HD model flies to monitor mHTT effects on innate immune response.

Country

Czech Republic

Related Organizations

National Library of Technology
Czech Republic

Keywords

Huntington disease; polyglutamine; Drosophila; adenosine

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