The epidemiology of femoral fractures is changing, with more femoral shaft fractures linked to high-risk physical exercise by an older population. Vitamin D given during pregnancy for the mother's health could benefit the child. Zoledronic acid is the most effective bisphosphonate. It should be given during hospitalization to people suffering from hip fractures. Denosumab should not be used in patients with severe renal failure. When denosumab is discontinued, management of the rebound effect requires bone resorption markers to be kept at very low levels to maintain the bone mass gained as much as possible. Finally, progress continues to be made in the treatment of rare bone diseases.