Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Repository of Instit...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Роль эритроцитов в генерации пуринергических агонистов и в воздействии лекарственных средств

Роль эритроцитов в генерации пуринергических агонистов и в воздействии лекарственных средств

Abstract

Рамазанов ВВ, Воловельская ЕЛ, Ершов СС, Ершова НА, Шапкина ОА, Руденко СВ, Бондаренко ВА. Роль эритроцитов в генерации пуринергических агонистов и в воздействии лекарственных средств. Теоретична і експериментальна медицина. 2017; 1 (74): 35-40 Створення ефективних лікарських засобів (ЛЗ) є основним напрямком у фармацевтичній науці та промисловості, який дозволить вирішити завдання, що залишаються невирішеними за допомогою існуючих стандартних методів терапії. У той же час, підхід до створення нових терапевтичних протоколів ще не вичерпав себе, фактично залишаючись основним у терапії судинних захворювань. Опубліковані дані щодо вивчення пуринергічної сигналізації в клітинах крові та судинах при різних захворюваннях свідчать про порушення фізіології еритроцитів, які поглиблюють судинний патогенез, тому ці клітини є потенційними клітинами-мішенями під дією МА, що може визначати нову терапевтичну стратегію для профілактики та лікування судинної патології. --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- The design of efficient medicinal agents (MAs) is the main direction in pharmaceutical science andindustry, which will solve the tasks still remaining unsolved with the current standard therapies. At thesame time, the approach to design the novel therapeutic protocols has not been exhausted yet, actuallyremaining a major one in therapy of vascular diseases. The reported data on studying the purinergicsignaling in blood cells and vessels under different diseases suggest a disorder in erythrocyte physiologyto aggravate the vascular pathogenesis, therefore these cells are potential target cells under MAs effect.This fact may determine a novel therapeutic strategy to prevent and treat vascular pathology.

Keywords

вазодилататоры, эритроциты, тромбоциты, антитромботические средства

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green