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Catalysts
Article . 2018 . Peer-reviewed
License: CC BY
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Catalysts
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Diastereoselective Synthesis of 7,8-Carvone Epoxides

Authors: Sofia Pombal; Ignacio E. Tobal; Alejandro M. Roncero; Jesus M. Rodilla; Narciso M. Garrido; Francisca Sanz; Alberto Esteban; +5 Authors

Diastereoselective Synthesis of 7,8-Carvone Epoxides

Abstract

The synthesis of the two 7,8-epoxides of carvone has been attained using organocatalysis in a two-step synthetic route through a bromoester intermediate. Among the different reaction conditions tested for the bromination reaction, moderate yields and diastereoselection are achieved using proline, quinidine, and diphenylprolinol, yielding the corresponding bromoesters that were transformed separately into their epoxides, obtaining the enantiopure products.

Keywords

carvone, epoxidation, epoxide, organocatalysis, aminocatalysis, proline

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
gold