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Allergen detection in dogs with atopic dermatitis using Prick

Authors: Coello Valdiviezo, Karina Rocío;

Allergen detection in dogs with atopic dermatitis using Prick

Abstract

Introducción: La dermatitis atópica canina (DAC)es una de las enfermedades cutáneas más habituales, su desarrollo está asociado a la producción de anticuerpos IgE-específicos, más comúnmente dirigidos frente a alergenos ambientales y de origen alimentario. Objetivos: El objetivo es establecer los alérgenos más comunes en perros clínicamente diagnosticados con dermatitis atópica utilizando la prueba de alergias denominada Prick Test, es una herramienta útil en el diagnóstico de una alergia mediada al detectar el alergeno desencadenante. Metodología: El estudio se realizó en el periodo Agosto - noviembre en la clínica Veterinaria Zoodoc; Veterinaria Metrópolis; y pacientes derivados de otras clínicas del Distrito Metropolitano de Quito, en una población de 20 perros, se recopilo datos sobre la historia clínica, incluyendo los síntomas observados, la duración de la enfermedad y posibles factores desencadenantes. Se colocaron 18 alérgenos en el flanco del paciente depilado en el mismo orden para todos los pacientes con los controles positivo (histamina) y negativo (diluyente) para observar la reacción. Interpretando las pruebas después de 15 a 20 minutos de la aplicación, definiéndose un resultado positivo como una roncha ≥3 mm de diámetro. El análisis estadístico consistió en determinar las frecuencias de cada alérgeno para todos los pacientes. Resultados: refleja la distribución de los casos en cada canino y su proporcionalidad con respecto a cada alérgeno. Del 100% de caninos, se puedo observar el 35% que tuvieron una respuesta a Insectos (30% de Pulex irritans (Pulga) y 5% Blattodea spp (Cucaracha)); 25% de los perros que respondieron a Ácaros (Dermatofagoides pteronnysinuy);20% que respondieron al Polen de Plantas (Grama (Cynodon dactylun));20% de Hongos (5% al Moho de Alimentos (Mucor spp.), 5% Aspergillius fuimigatus, 5% Candida spp. y 5% Moho de Humedad (Hormodendro spp)) y con el 5% equivalente a la respuesta de Inhalantes (Lana de Gato). Frente a Alimentos ningún perro presento respuesta. Conclusión: Todos los alérgenos pertenecientes a los grupos de insectos ácaros, hongos y pólenes provocaron reacciones en los perros estudiados. No se observó una relación entre la edad de los pacientes y los alérgenos probados. Área de estudio general: Medicina Veterinaria. Área de estudio especifica: Dermatología canina. Tipo de estudio: original.

Introduction: Canine atopic dermatitis (CAD) is one of the most common skin diseases. Its development is associated with the production of IgE-specific antibodies, most commonly directed against environmental and food-based allergens. Objectives: The objective is to establish the most common allergens in dogs clinically diagnosed with atopic dermatitis using the allergy test called Prick Test, it is a useful tool in the diagnosis of a mediated allergy by detecting the triggering allergen. Methodology: The study was carried out in the period August - November at the Zoodoc Veterinary clinic; Metropolis Veterinary; and patients referred from other clinics in the Metropolitan District of Quito, in a population of 20 dogs, data on the clinical history was collected, including the symptoms observed, the duration of the disease and possible triggering factors. 18 allergens were placed on the flank of the depilated patient in the same order for all patients with the positive (histamine) and negative (diluent) controls to observe the reaction. Interpreting the tests after 15 to 20 minutes of application, defining a positive result as a wheal ≥3 mm in diameter. The statistical analysis consisted of determining the frequencies of each allergen for all patients. Results: reflects the distribution of cases in each canine and its proportionality with respect to each allergen. Of the 100% of canines, it was possible to observe 35% that had a response to Insects (30% Pulex irritans (Flea) and 5% Blattodea spp (Cockroach)); 25% of dogs that responded to Mites (Dermatofagoides pteronnysinuy); 20% that responded to Plant Pollen (Grass (Cynodon dactylun)); 20% to Fungi (5% to Food Mold (Mucor spp.), 5% Aspergillius Fuimigatus, 5% Candida spp. and 5% Damp Mold (Hormodendron spp)) and with 5% equivalent to the response of Inhalants (Cat's Wool). Regarding Food, no dog presented a response. Conclusion: All allergens belonging to the groups of insects, mites, fungi and pollens caused reactions in the dogs studied. No relationship was observed between the age of the patients and the allergens tested. General Study Area: Veterinary Medicine. Specific area of ​​study: Canine dermatology. Study type: original.

Keywords

Alérgenos, Dermatitis, Pacientes Atópicos, Reacción Cutánea., Allergens, Dermatitis, Atopic Patients, Skin Reaction.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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Average
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