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EOSINOPHILIC ESOPHAGITIS IN A BOY OF 10 YEARS. CLINICAL CASE

Authors: Macharadze D.Sh.; Larkova I.A.; Revjakina V.A.; Peshkin V.I.; Sadikov I.S.;

EOSINOPHILIC ESOPHAGITIS IN A BOY OF 10 YEARS. CLINICAL CASE

Abstract

Эозинофильный эзофагит (ЭоЭ) относится к группе гастроинтестинальных эозинофильных заболеваний, которую крайне редко диагностируют в реальной клинической практике российские врачи, особенно у детей. Изначально ЭоЭ считали преимущественно детским заболеванием. ЭоЭ следует заподозрить у пациентов с аллергическими заболеваниями (чаще всего мужского пола) и в сочетании с дисфагией и/или другими жалобами со стороны желудочно-кишечного тракта. Со временем и, особенно при неадекватной терапии, ЭоЭ сопровождается формированием стриктур и фиброзными изменениями ткани пищевода. ЭоЭ - клинико-морфологический диагноз, требующий проведения биопсии слизистой оболочки пищевода. Эта процедура позволяет выявить повышение уровня эозинофилов (≥15 в поле зрения, х400) в пищеводной ткани (без других альтернативных причин эозинофилии). Здесь мы представляем возможный случай ЭоЭ у мальчика 10 лет, страдающего персистирующим аллергическим ринитом, поллинозом, пищевой аллергией и периодически - обострением атопического дерматита.

Eosinophilic esophagitis (EoE) belongs to the group of gastrointestinal eosinophilic diseases, which is rarely diagnosed in real clinical practice by Russian doctors, especially in children. Initially, EoE was considered a predominantly childhood disease. EoE should be suspected in patients with allergic diseases (most often male) and in combination with dysphagia and/or other complaints from the gastrointestinal tract. Over time and, especially, with inadequate therapy, EoE is accompanied by the formation of strictures and fibrous changes in the esophageal tissue. EoE is a clinical and morphological diagnosis, which requires a biopsy of the esophageal mucosa, which reveals an increase in the level of eosinophils (≥15 in sight, x 400) in the esophageal tissue (without other alternative causes of eosinophilia).

Keywords

eosinophilic esophagitis, clinical case, children, treatment, diagnosis, эозинофильный эзофагит, диагностика, дети, лечение, клинический случай

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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