Alcoholism is a severe chronic mental illness, often subordinating all aspects of the patient’s life and quickly leading to social degradation. In recent years we observed a certain change in the attitude towards the classical therapeutic approach, which implies a complete abstention from alcohol intake. This was due to the research on pharmacological agents that can affect the brain reinforcement system, thereby reducing craving and decreasing the amount of alcohol consumed. This article describes a clinical case of changing the pattern of alcohol abuse during the use of opioid receptor antagonist naltrexone in the form of injections for the treatment of a patient with severe alcohol dependence, resistant to psychopharmacotherapy. The effectiveness and duration of the treatment course is determined primarily by patients’ motivation or by the interest of persons close to the patient.

В данной статье описан клинический случай применения антагониста опиоидных рецепторов налтрексона пролонгированного действия в форме инъекций для лечения пациента с тяжелым случаем алкогольной зависимости, резистентной к психофармакотерапии. Эффективность и продолжительность курса лечения, определяется в первую очередь, мотивацией больных либо заинтересованностью близких пациенту лиц.