
Main clinical-pharmacological effects of dipiridamol action are considered in the context of its use in case of cerebrovascular disease. The vasodilatating effect of the medicine, antioxidative effect and ability to improve tissue perfusion are accentuated. The results of experimental and clinical research work reflecting efficacy and safety of dipiridamol are introduced. Pleiotropic action mechanism of the medicament whicht makes it possible to have a complex influence at pathogenetic factors of cerebrovascular disease is noted.
Рассмотрены основные клинико-фармакологические эффекты дипиридамола в контексте его применения при цереброваскулярной болезни. Сделан акцент на вазодилатирующем действии препарата, его способности улучшать перфузию тканей и антиоксидантном эффекте. Приведены результаты экспериментальных и клинических исследований, отражающих эффективность и безопасность дипиридамола. Отмечен плейотропный механизм действия препарата, позволяющий достичь комплексного воздействия на патогенетические факторы цереброваскулярной болезни.
плейотропные эффекты, dipyridamole, антиагреганты, antiaggregants, pleiotropic effects, дипиридамол
плейотропные эффекты, dipyridamole, антиагреганты, antiaggregants, pleiotropic effects, дипиридамол
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