
Analizom parnih seruma metodom indirektne imunofluorescencije (IFA) dokazana su protutijela za Rickettsia conorii u 64 (51,6%) od 124 ispitanika s ubodom krpelja u sjevernodalmatinskoj regiji (Hrvatska) tijekom 1994. i 1995. godine. Protutijela za R. conorii dokazana su u 12 (31,5%) od 38 ispitanika s provedenom profilaksom azitromicinom nakon uboda krpelja i u 52 (60,5%) od 86 ispitanika bez provedene profilakse. Klinička slika mediteranske pjegave groznice razvila se u 22 (25,6%), a asimptomatska infekcija u 30 (34,8%) od 86 ispitanika bez profilakse. Kliničke manifestacije bolesti nisu zabilježene ni u jednog ispitanika s provedenom profilaksom.
azithromycin, mediteranska pjegava groznica, azitromicin, boutonneuse fever
azithromycin, mediteranska pjegava groznica, azitromicin, boutonneuse fever
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