
of MPV after 7 days postinfection, applying peroral administration once within 24 hours (24 hours before infection and 7 days after infection of mouse with 60 µg/g of a preparation). Displayed is the feasibility of using 8–15-days-old ICR mice (body weight 9–11 g) as an animal model for evaluation of therapeutic efficacy of the preparations under development against Monkeypox and smallpox.
50 % infective dose, animal model, intranasal infection, вирус оспы обезьян, Infectious and parasitic diseases, RC109-216, мышь, модельное животное, monkeypox virus, preparations against monkeypox, противооспенные препараты, клинические признаки, clinical signs, 50 % инфицирующая доза, интраназальное инфицирование, mouse
50 % infective dose, animal model, intranasal infection, вирус оспы обезьян, Infectious and parasitic diseases, RC109-216, мышь, модельное животное, monkeypox virus, preparations against monkeypox, противооспенные препараты, клинические признаки, clinical signs, 50 % инфицирующая доза, интраназальное инфицирование, mouse
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