
AbstractThe degenerative motor neuron disorder amyotrophic lateral sclerosis (ALS) frequently leads bulbar symptoms like dysarthria, dysphagia, and sialorrhea, in approximately one-third of cases being the initial symptom. Throughout the disease, more than two-thirds of ALS patients experience dysphagia, regardless of the region of onset. In this review, we aimed to offer an updated overview of dysphagia and sialorrhea in ALS, covering its diagnosis, monitoring, and treatment in clinical practice. Regular assessment of dysphagia and sialorrhea during each patient visit is essential and should be a standard aspect of ALS care. Early discussion of potential treatments such as high-calorie diets or percutaneous endoscopic gastrostomy (PEG) is crucial. Furthermore, this review highlights and discusses potential areas for improvement in both clinical practice and research.
Amyotrophic lateral sclerosis ; Sialorrhea/therapy [MeSH] ; Humans [MeSH] ; Sialorrhea ; Dysphagia ; Disease Management [MeSH] ; Amyotrophic Lateral Sclerosis/diagnosis [MeSH] ; Amyotrophic Lateral Sclerosis/complications [MeSH] ; Motor neuron disease ; Deglutition Disorders/physiopathology [MeSH] ; Sialorrhea/diagnosis [MeSH] ; Sialorrhea/etiology [MeSH] ; ALS ; Deglutition Disorders/therapy [MeSH] ; Review ; Deglutition Disorders/diagnosis [MeSH] ; Amyotrophic Lateral Sclerosis/therapy [MeSH] ; Deglutition Disorders/etiology [MeSH], Amyotrophic Lateral Sclerosis, Humans, Disease Management, Review, Sialorrhea, Deglutition Disorders
Amyotrophic lateral sclerosis ; Sialorrhea/therapy [MeSH] ; Humans [MeSH] ; Sialorrhea ; Dysphagia ; Disease Management [MeSH] ; Amyotrophic Lateral Sclerosis/diagnosis [MeSH] ; Amyotrophic Lateral Sclerosis/complications [MeSH] ; Motor neuron disease ; Deglutition Disorders/physiopathology [MeSH] ; Sialorrhea/diagnosis [MeSH] ; Sialorrhea/etiology [MeSH] ; ALS ; Deglutition Disorders/therapy [MeSH] ; Review ; Deglutition Disorders/diagnosis [MeSH] ; Amyotrophic Lateral Sclerosis/therapy [MeSH] ; Deglutition Disorders/etiology [MeSH], Amyotrophic Lateral Sclerosis, Humans, Disease Management, Review, Sialorrhea, Deglutition Disorders
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