Cyber-Physical Systems (CPS) have the promise of presenting the next evolution in computing with potential applications that include aerospace, transportation, and various automation systems. These applications motivate advances in the different sub-fields of CPS such as mobile computing, context awareness, and computer vision. However, deploying and testing complete CPSs is known to be a complex and expensive task. In this paper, we present the design, implementation, and evaluation of Up and Away (UnA): a testbed for Cyber-Physical Systems that use Unmanned Aerial Vehicles (UAVs) as their main physical component. UnA aims to abstract the control of physical system components to reduce the complexity of UAV oriented CPS experiments. UnA provides APIs to allow for converting CPS algorithm implementations, developed typically for simulations, into physical experiments using a few simple steps. We present two scenarios of using UnA’s API to bring mobile-camera-based surveillance algorithms to life, thus exhibiting the ease of use and flexibility of UnA.