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Journal of Clinical Microbiology
Article . 2022 . Peer-reviewed
License: CC BY
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Article . 2022
License: CC BY
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Validation of Fourier Transform Infrared Spectroscopy for Serotyping of Streptococcus pneumoniae

Authors: Passaris, I.; Mauder, N.; Kostrzewa, M.; Burckhardt, I.; Zimmermann, S.; van Sorge, N.M.; Slotved, H-C.; +2 Authors

Validation of Fourier Transform Infrared Spectroscopy for Serotyping of Streptococcus pneumoniae

Abstract

Fourier transform infrared (FT-IR) spectroscopy (IR Biotyper; Bruker) allows highly discriminatory fingerprinting of closely related bacterial strains. In this study, FT-IR spectroscopy-based capsular typing of Streptococcus pneumoniae was validated as a rapid, cost-effective, and medium-throughput alternative to the classical phenotypic techniques.

Countries
Netherlands, Belgium
Keywords

PUBLIC-HEALTH IMPACT, ENGLAND, IMMUNOGENICITY, Serogroup, Microbiology, DISEASE, Pneumococcal Infections, COMPLEMENT, 07 Agricultural and Veterinary Sciences, Spectroscopy, Fourier Transform Infrared, EPIDEMIOLOGY, Humans, Serotyping, Pneumococcal Infections/diagnosis, 11 Medical and Health Sciences, Science & Technology, Bacteria, 3202 Clinical sciences, CAPSULE, Bacteriology, ADULTS, Serotyping/methods, 06 Biological Sciences, 3207 Medical microbiology, serotyping, machine learning, Streptococcus pneumoniae, Spectroscopy, Fourier Transform Infrared/methods, PNEUMOCOCCAL CONJUGATE VACCINE, SAFETY, FT-IR spectroscopy, Life Sciences & Biomedicine, pneumococcus

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    29
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
29
Top 10%
Top 10%
Top 10%
Green
gold