Australian-born Raymond Dart arrived in South Africa in 1922 and subsequently gave the name Australopithecus africanus to the fossilised juvenile skull discovered by mine workers in Taung, North West Province. After this discovery, and its announcement in 1925, the discipline of palaeoanthropology grew exponentially on the continent. This centennial milestone necessitates reflection on the role of science in society, with a critical look at the relationship between palaeosciences, the theories of human evolution, and the researcher’s interaction with southern African Indigenous peoples. Here we examine the palaeoanthropological scientific practice in southern Africa and suggest ways to decolonise science, and its narratives, in the future. To achieve meaningful transformation and social cohesiveness, we discuss measures to counter the wrongs of the past through meaningful and socially responsive practices such as equitable funding schemes, meaningful collaboration, and doing away with ‘helicopter research’.