
pmid: 27013120
Postoperative cognitive decline (POCD) has a perceivable influence on daily living and is noticed more often by close relatives than by patients themselves 3 months after aortic valve replacement. This study aimed to elucidate the longitudinal course of the subjective awareness of POCD.Follow-up of a prospective observational study.A single cardiothoracic center in Germany.The study included 108 patients scheduled for elective aortic valve replacement surgery and 85 close relatives of the patients.In addition to conducting a neuropsychologic examination, the authors previously interviewed 82 patients with a Cognitive Failure Questionnaire for self-assessment (s-CFQ), and 62 relatives with the Cognitive Failure Questionnaire for others (f-CFQ) before and 3 months after surgery. Up until 12 months after surgery, the authors continuously interviewed additional patients (baseline and 3 months after surgery), thereby enlarging the original sample, and included the entire group (108 patients, 85 relatives) for the 12-month follow-up.The analysis showed that relatives (p = 0.026) and patients experienced patients' cognitive decline 3 months after surgery (p = 0.009). All changes still were observed in questions related to memory and attention. After 1 year, the s-CFQ no longer differed between baseline and postoperative assessment. Mean scores in the f-CFQ still were above baseline, barely missing statistical significance (p = 0.051). In patients with "change to worse" in the f-CFQ at 1-year follow-up, declining cognitive results in nonverbal learning (p = 0.021) could be observed 3 months postoperatively. Only a decrease in 3-month f-CFQ correlated with a decline in specific neuropsychologic tests 3 months after surgery.Contrary to the authors' previous results, the impact of POCD on daily living functions also was recognized by the patients themselves. The long-term influence and the associations between subjective deficits and psychometric cognitive measures seemed to be assessed more reliably by close relatives.
Aged, 80 and over, Heart Valve Prosthesis Implantation, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, Memory, Aortic Valve, Surveys and Questionnaires, Activities of Daily Living, Humans, Attention, Cognitive Dysfunction, Female, Prospective Studies, Aged, Follow-Up Studies
Aged, 80 and over, Heart Valve Prosthesis Implantation, Male, Middle Aged, Neuropsychological Tests, Postoperative Complications, Memory, Aortic Valve, Surveys and Questionnaires, Activities of Daily Living, Humans, Attention, Cognitive Dysfunction, Female, Prospective Studies, Aged, Follow-Up Studies
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