The article is devoted to the study of the interaction of entrepreneurial and power structures in the context of the implementation of the project “New Silk Road”. Attention is focused on the fact that the basis for the development of all areas of development of this project in each individual country should be systemic state support and appropriate budget programs. Consistent and logical application of scientific methods: from theoretical generalization to modeling, it was possible to determine the spheres of interaction between business and the state when implementing budget programs (for example, the purpose of trade development within the framework of the New Silk Road project). Within the framework of the research, the primary tasks aimed at ensuring the development of interaction between power and business structures are predetermined, based on the balance of social and economic interests.