Introducing semantics into the Internet of Things (IoT) has been attracting increasing attention from researchers and industrial practitioners. Interoperability stays a critical weight to the engineers of the Internet of Things Systems. This is because of the way that the IoT gadgets are exceptionally heterogeneous as far as fundamental correspondence protocol, information organizations, and advances. Our spotlight in this section is on information semantics, liable for definition, the board, and preparing of information. The Internet of Things (IoT), true to form the foundation for the imagined idea of Smart structure, brings new conceivable outcomes for the structure of the executives. IoT vision presents promising and practical answers for gigantic information assortment and its investigation which can be applied in numerous areas thus cause them to work all the more productively. End-user development programming environments in the IoT enable end-users to customize their IoT objects’ joint behavior, typically via IFTTT trigger-action rules. Aim of the chapter to propose an IoT based Semantic Interoperability Model with EUPont Semantic Web ontology to provide Semantic Interoperability among heterogeneous IoT devices for control of end-user applications.