Coagulopathy in Acute Puumala Hantavirus Infection
Copyright policy )Coagulopathy in Acute Puumala Hantavirus Infection
Puumala hantavirus (PUUV) causes a hemorrhagic fever with renal syndrome (HFRS), also called nephropathia epidemica (NE), which is mainly endemic in Europe and Russia. The clinical features include a low platelet count, altered coagulation, endothelial activation, and acute kidney injury (AKI). Multiple connections between coagulation pathways and inflammatory mediators, as well as complement and kallikrein–kinin systems, have been reported. The bleeding symptoms are usually mild. PUUV-infected patients also have an increased risk for disseminated intravascular coagulation (DIC) and thrombosis.
endothelium, Puumala hantavirus, Review, 3121 Internal medicine, Microbiology, Puumala virus, Russia, DIC, LONG PENTRAXIN PTX3, THROMBIN GENERATION, coagulation, complement system, 11832 Microbiology and virology, platelet, NITRIC-OXIDE, THROMBOCYTOPENIA, Thrombosis, Acute Kidney Injury, Blood Coagulation Disorders, Disseminated Intravascular Coagulation, ENDOTHELIAL-CELLS, QR1-502, NEPHROPATHIA-EPIDEMICA, Europe, RENAL SYNDROME, Biomedicine, HEMORRHAGIC-FEVER, acute kidney injury, Hemorrhagic Fever with Renal Syndrome, Acute Disease, INNATE IMMUNITY, fibrinolysis, COMPLEMENT ACTIVATION
endothelium, Puumala hantavirus, Review, 3121 Internal medicine, Microbiology, Puumala virus, Russia, DIC, LONG PENTRAXIN PTX3, THROMBIN GENERATION, coagulation, complement system, 11832 Microbiology and virology, platelet, NITRIC-OXIDE, THROMBOCYTOPENIA, Thrombosis, Acute Kidney Injury, Blood Coagulation Disorders, Disseminated Intravascular Coagulation, ENDOTHELIAL-CELLS, QR1-502, NEPHROPATHIA-EPIDEMICA, Europe, RENAL SYNDROME, Biomedicine, HEMORRHAGIC-FEVER, acute kidney injury, Hemorrhagic Fever with Renal Syndrome, Acute Disease, INNATE IMMUNITY, fibrinolysis, COMPLEMENT ACTIVATION
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).22 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!