This paper focuses on two integration algorithms used for pseudo-dynamic test, explicit Newmark algorithm and implicit alpha-C algorithm. The comparison study between the test and simulation results shows that: the non-uniform distribution of mass, restoring force characteristics and higher frequency vibration modality are simulated more accurately using the alpha-C algorithm than using explicit Newmark algorithm. The alpha-C algorithm also leads to high iterative accuracy and unconditional stability. Replacing the explicit Newmark algorithm in original experimental system by implicit alpha-C algorithm, the MDOF pseudo dynamic test system can be realized successfully.