Here we present current data on the mechanisms of development, clinical symptoms, diagnosis and treatment of intestinal ischemia on a clinical case of erosive ulcerative ischemic colitis in a 67-year-old male patient. The need for awareness on chronic mesenterial ischemia in risk groups is underlined. A particular attention is paid to the non-specificity of clinical manifestations in comorbid patients. In elderly and senile patients, any change in abdominal symptoms is a subject for intestinal ischemia screening.