The objective was to compare physic-mechanical properties of different materials used for temporary restorations.Protemp 4/bisacrylic resin, Jet/acrylic resin, and Nexdent C&B/3D-printed resin samples (10mm diameter x 2mm thickness) were analyzed for surface roughness and color stability tests (baseline, after 5 thousand brushing cycles; and after artificial aging in water at 60oC for 24 hours) and Knoop microhardness. All data were checked for normality using Shapiro-Wilk test. Surface roughness and color stability were analyzed using two-way repeated measurements ANOVA, microhardness data was subjected to one-way ANOVA. All tests were followed by Tukey test and were performed with α=0.05.For roughness, material (p=.002), time points (p=.002) and interaction between both (p<.001) were significant. All groups presented similar roughness for measurements of baseline and after brushing. After artificial aging, 3D printed resin showed decreased roughness when compared with other resins, and with its baseline reading. Acrylic resin showed an increase in surface roughness (when compared with measurement after brushing cycles). Considering color stability, only the material (p=.039) and the time (p<0.001) were significant. All groups showed similar color variation before and after artificial aging. There was an increase in color alteration after artificial aging for all groups. Considering microhardness test (p<.001), the 3D printed resin showed the highest values and acrylic resin the lowest. Bysacylic resin was similar to both 3D printed and acrylic resins.The tested 3D printed resins present similar or better properties than other tested temporary materials while being integrated with the digital workflow. Key words:Disinfection methods, hydroxyl radical, environment, surfaces, dentistry.