The paper presents a comparative analysis of the classical suture surgical method and biological method of welding of live tissues. On the basis of clinical studies, it has been established that the biological welding of live tissues is more effective, which is confirmed by the obtained results. The purpose of the study. To study the advantage of the method of high frequency electric welding of living tissue over other methods of connecting tissue, during surgical interventions of the oral cavity, by comparison with the classical surgical method. Material and methods. We examined and treated twenty patients with cysts of the jaws who underwent dental consultation at the department of Educational-medical centre "University clinic". All patients were between 25 and 45 years without concomitant disease under normal working and nutritional conditions and without oral pathology. In all cases, the changes covered no more than two teeth, cysts did not extend to the nasal cavity, maxillary sinus, and mandibular canal. Twelve of the twenty patients formed a comparison group and were treated with classical surgical method. Patients not included in the comparison group, were in the main group, where instead of suture material, we used a method of welding tissue. Results. It has been established that the method of using the apparatus for high frequency electric welding of live tissues of EKVZ-300 "PATENTED" provides a complete, tight and airtight closure of wounds. The use of electroservices in the surgical treatment of cancer patients does not impair the immunological resistance of the organism, and contributes to the activation of mechanisms of anticancer immunity, namely, increases destructive capacity of natural cytotoxic cells almost in 2 times. The performing surgery with the use of welding apparatus creates optimal conditions for rapid healing of wound due to less trauma to the tissues, the lack of foreign suture material in the wound, reducing the duration of surgery and time of drug activity in the body. Conclusions. Using the method of high-frequency welding of tissue during cystectomy in the oral cavity significantly reduces operation time in comparison with surgical, reduces trauma of the tissues, ensures the integrity of the wound, reduces the cost of suture materials, 90% reduces the risk of wound infection. In the wound no foreign bodies (sutures, staples, glue, etc.), that allows to avoid such complications as bleeding and purulent inflammation of the wound. After healing, we observed absence of seams due to ingrowth of blood vessels and resumption of blood flow.