Synthesis and antifungal activity of benzofuran-5-ols

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2010 English Publisher:Elsevier BVJournal:Bioorganic & Medicinal Chemistry Letters, volume 20, pages 6,777-6,780 (issn: 0960-894X,

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Authors: Chung-Kyu, Ryu; Ae Li, Song; Jung Yoon, Lee; Jung An, Hong; Joo Hee, Yoon; Aram, Kim;

doi: 10.1016/j.bmcl.2010.08.129

pmid: 20851600

Synthesis and antifungal activity of benzofuran-5-ols

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Abstract

Benzofuran-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many benzofuran-5-ols showed good antifungal activity. The results suggest that benzofuran-5-ols would be promising antifungal agents.

Related Organizations

Ewha Womans University
Korea (Republic of)

Keywords

Antifungal Agents, Aspergillus, Cryptococcus neoformans, Microbial Sensitivity Tests, Benzofurans, Candida

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