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Journal of Applied Physiology
Article . 2024 . Peer-reviewed
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Motor-evoked potentials in the human upper and lower limb do not increase after single 30-min sessions of acute intermittent hypoxia

Authors: Anandit J. Mathew; Harrison T. Finn; Sophie G. Carter; Simon C. Gandevia; Jane E. Butler;

Motor-evoked potentials in the human upper and lower limb do not increase after single 30-min sessions of acute intermittent hypoxia

Abstract

This is the first study that tests whether acute intermittent hypoxia (AIH) induces motor output facilitation in humans after two different doses of AIH (9% and 12% [Formula: see text]) and the reproducibility of participant responses after a repeat AIH intervention at 9% AIH. There was no motor output facilitation in response to either dose of AIH. The results question the effectiveness of a single 30-min session of AIH in inducing motor output facilitation, tested in this way.

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Keywords

Male, Adult, Physical Injury - Accidents and Adverse Effects, Clinical Trials and Supportive Activities, intermittent hypoxia, Pyramidal Tracts, 610, 32 Biomedical and Clinical Sciences, Upper Extremity, Young Adult, anzsrc-for: 32 Biomedical and Clinical Sciences, Clinical Research, anzsrc-for: 31 Biological sciences, 9% [Formula: see text] AIH, Humans, Spinal Cord Injury, Hypoxia, Muscle, Skeletal, 3202 Clinical Sciences, Evoked Potentials, Traumatic Head and Spine Injury, Spinal Cord Injuries, anzsrc-for: 42 Health Sciences, Cross-Over Studies, Rehabilitation, Neurosciences, 42 Health Sciences, 3 Good Health and Well Being, Skeletal, Evoked Potentials, Motor, Transcranial Magnetic Stimulation, serotonin, Motor, anzsrc-for: 11 Medical and Health Sciences, Lower Extremity, anzsrc-for: 06 Biological Sciences, Muscle, anzsrc-for: 3202 Clinical Sciences, Female, 12% [Formula: see text] AIH, motor-evoked potentials

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Top 10%
Average
Top 10%
Green